Monitor Intently (1)pentobarbital will minimize the level or impact of fentanyl transdermal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on to some minimize in fentanyl plasma concentrations, lack of efficacy or, possibly, improvement of a withdr… Read More